Unable to run new virus guard setup file

I have tried several free virus guard installations but all of them not working even did not run the setup file. I know this will due to virus attacks but i want to know how to clean them? & how to install a virus guard without help of other computer or device?

You can try Kaspersky rescue disk .

https://www.kaspersky.com/downloads/thank-you/free-rescue-disk

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thank you.done